Thymosin Alpha-1
Thymic peptide (28 amino acids). ≥99% purity. 3mg lyophilized. TLR2/TLR9 agonist. Approved in 35+ countries as Zadaxin for immunomodulation.
100 in stock
Overview
Thymosin Alpha-1 (Ta1) is a 28-amino acid thymic peptide naturally produced by the thymus gland. Approved as Zadaxin in over 30 countries outside the United States for various research applications.
Published Research
Published literature has examined Thymosin Alpha-1 across multiple research contexts:
- T-cell maturation and differentiation pathway research
- Dendritic cell activation and antigen presentation studies
- NK cell activity modulation in preclinical immune models
- Toll-like receptor signaling and innate immune response research
| Molecular Formula | C129H215N33O55 |
|---|---|
| Molecular Weight | 3108.27 g/mol |
| Monoisotopic Mass | 3107.49 Da |
| CAS Number | 61512-21-8 |
| Amino Acid Count | 28 |
| Sequence | Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn |
| Purity | ≥99.0% (HPLC verified) |
| Physical Form | White lyophilized powder |
| Storage | -20°C recommended, protect from light |
| PubChem CID | 44286042 |
| SKU | TA1-5MG |
• Immunomodulation: Extensive research on Tα1's effects on T-cell maturation, NK cell activity, and dendritic cell function (Tuthill et al., 2010).
• Infectious disease models: Studies examining Tα1 in hepatitis B and C models, including clinical trials in several countries.
• Cancer immunology: Research on Tα1 as an immunoadjuvant in preclinical tumor models.
• Vaccine adjuvant research: Studies examining Tα1's ability to enhance vaccine immunogenicity.
Standard reconstitution: 1 mL bacteriostatic water per vial unless otherwise specified on the Certificate of Analysis. Store reconstituted solution at 2-8°C and use within 30 days. Lyophilized powder stable at -20°C for 24 months when sealed under inert atmosphere.
- Purity (HPLC)
- 99%
- Identity (MS)
- 3108.27 g/mol (theoretical)
Every vial of this lot carries this lot number and a QR code that resolves to the same page. Values are lot-specific analytical results; representative specifications are on the Specifications tab.
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