Thymosin Alpha-1
CAS
61512-21-8
Formula
C129H215N33O55
MW
3108.27 g/mol
Sequence
Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn
Form
White lyophilized powder
Storage
-20°C recommended, protect from light
Purity
≥99.0% HPLC
Tissue Biology Research

Thymosin Alpha-1

Thymic peptide, 28 amino acids. ≥99% purity. TLR2/TLR9 agonist studied in immune-signalling research.

99% HPLCLot AUR-2025-TA1Certificate of Analysis ↗
$46.00

In stock

For Research Purposes Only • Not For Human Consumption

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  • Lot number on your order line
  • Dispatched from the United States

Packs of 10 vials: $27.60 each after 3 orders (Atelier) · $23.00 each after 6 orders (Laboratory)

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Be told when the next tested lot of Thymosin Alpha-1 is released: the certificate link the moment it posts, and a 48-hour early window with 5% off that lot. One message per lot, nothing else.

For Research Use Only (RUO). Not for human or veterinary use. Not for diagnostic or therapeutic purposes. Not approved by the FDA. By purchasing, you acknowledge research-only intent.
✓99.0%+ HPLC Verified ✓Certificate of Analysis Included ✓Lyophilized for Stability ✓Same-Day Dispatch by 2 PM ET ✓SKU: TA1-5MG

Overview

Thymosin Alpha-1 (Ta1) is a 28-amino acid thymic peptide naturally produced by the thymus gland. Approved as Zadaxin in over 30 countries outside the United States for various research applications.

Published Research

Published literature has examined Thymosin Alpha-1 across multiple research contexts:

  • T-cell maturation and differentiation pathway research
  • Dendritic cell activation and antigen presentation studies
  • NK cell activity modulation in preclinical immune models
  • Toll-like receptor signaling and innate immune response research
Chemical Profile · Analytical Specifications
Molecular FormulaC129H215N33O55
Molecular Weight3108.27 g/mol
Monoisotopic Mass3107.49 Da
CAS Number61512-21-8
Amino Acid Count28
SequenceAc-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn
Purity≥99.0% (HPLC verified)
Physical FormWhite lyophilized powder
Storage-20°C recommended, protect from light
PubChem CID44286042
SKUTA1-5MG
Analytical data. Specifications reflect typical lot characteristics. Lot-specific values appear on the Certificate of Analysis shipped with each order. View the current lot certificate →

• Immunomodulation: Extensive research on Tα1's effects on T-cell maturation, NK cell activity, and dendritic cell function (Tuthill et al., 2010).
• Infectious disease models: Studies examining Tα1 in hepatitis B and C models, including clinical trials in several countries.
• Cancer immunology: Research on Tα1 as an immunoadjuvant in preclinical tumor models.
• Vaccine adjuvant research: Studies examining Tα1's ability to enhance vaccine immunogenicity.

Standard reconstitution: 1 mL bacteriostatic water per vial unless otherwise specified on the Certificate of Analysis. Store reconstituted solution at 2-8°C and use within 30 days. Lyophilized powder stable at -20°C for 24 months when sealed under inert atmosphere.

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Every lot ships with a third-party HPLC certificate. View the most recent lot certificate via the COA Portal. Mass spectrometry confirmation available on request.

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RESEARCH USE ONLY (RUO). Not for human or veterinary use. Not for consumption of any kind. Not for use in the diagnosis, treatment, cure, or prevention of any disease or condition. Not approved by the FDA. All products are sold exclusively to qualified research professionals aged 21 or older, for in-vitro laboratory research purposes only.No statement on this website has been evaluated by the FDA. By purchasing you confirm you are a qualified researcher and accept our Terms. California Proposition 65: products may contain chemicals known to the State of California to cause cancer or reproductive harm. P65Warnings.ca.gov

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