BPC-157
Synthetic pentadecapeptide (15 amino acids) from human gastric juice protein. ≥99% purity, HPLC verified. 5mg lyophilized. Studied for tissue protection and repair biology in preclinical models.
Overview
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide (15 amino acids). Over 140 peer-reviewed studies indexed on PubMed. First isolated from human gastric juice and described in 1993.
Published Research
Published literature has examined BPC-157 across multiple research contexts:
- Interaction with the nitric oxide (NO) system and VEGF expression in preclinical models
- Effects on tendon fibroblast activity and collagen formation pathways
- Gastric pentadecapeptide stability in various pH environments without carrier molecules
- Interaction with growth factor pathways including EGF, FGF, and NGF
| Molecular Formula | C62H98N16O22 |
|---|---|
| Molecular Weight | 1419.53 g/mol |
| Monoisotopic Mass | 1418.7 Da |
| CAS Number | 137525-51-0 |
| Amino Acid Count | 15 |
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val |
| Purity | ≥99.2% (HPLC verified) |
| Physical Form | White lyophilized powder |
| Storage | -20°C recommended, protect from light |
| PubChem CID | 9941957 |
| SKU | BPC157 |
Published preclinical research on BPC-157 has explored its effects in multiple experimental models:
• Gastrointestinal biology: Studies in animal models have examined BPC-157's effects on gastric mucosal integrity, intestinal anastomosis healing, and inflammatory bowel models (Sikiric et al., 2018).
• Musculoskeletal biology: Preclinical investigations have assessed BPC-157 in tendon, ligament, and muscle injury models, examining parameters such as collagen fiber organization and biomechanical strength (Chang et al., 2011).
• Vascular biology: Research has explored BPC-157's interaction with the NO system and angiogenic pathways in various tissue repair models (Hsieh et al., 2017).
• Neuroprotective research: Studies have investigated BPC-157 in models of peripheral nerve injury and dopaminergic system modulation (Klicek et al., 2013).
Standard reconstitution: 1 mL bacteriostatic water per vial unless otherwise specified on the Certificate of Analysis. Store reconstituted solution at 2-8°C and use within 30 days. Lyophilized powder stable at -20°C for 24 months when sealed under inert atmosphere.
Every lot ships with a third-party HPLC certificate. View the most recent lot certificate via the COA Portal. Mass spectrometry confirmation available on request.
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