NAD+
Essential cellular coenzyme (MW 663.43). ≥99% purity. 500mg. Sirtuin substrate and electron carrier. Critical for mitochondrial function and cellular metabolism.
Overview
NAD+ (Nicotinamide Adenine Dinucleotide) is a essential coenzyme found in all living cells. One of the most studied molecules in longevity research. Central to cellular energy metabolism.
Published Research
Published literature has examined NAD+ across multiple research contexts:
- Sirtuin enzyme activation (SIRT1-7) and epigenetic regulation
- Cellular energy metabolism via electron transport chain
- DNA repair mechanisms (PARP enzyme substrate)
- Longevity biomarker research across hundreds of published studies
| Molecular Formula | C21H27N7O14P2 |
|---|---|
| Molecular Weight | 663.43 g/mol |
| Monoisotopic Mass | 663.11 Da |
| CAS Number | 53-84-9 |
| Purity | ≥99.5% (HPLC verified) |
| Physical Form | White lyophilized powder |
| Storage | -20°C recommended, protect from light |
| PubChem CID | 5892 |
| SKU | NAD |
• Sirtuin biology: Research on NAD+ as a substrate for SIRT1-SIRT7 deacetylases and their roles in gene regulation and metabolism (Imai & Guarente, 2014).
• Aging research: Studies examining the NAD+ decline hypothesis and supplementation strategies.
• DNA repair: Research on PARP enzyme activity and NAD+ consumption during DNA damage repair.
• Metabolic research: Studies on NAD+ roles in glycolysis, TCA cycle, and oxidative phosphorylation.
Standard reconstitution: 1 mL bacteriostatic water per vial unless otherwise specified on the Certificate of Analysis. Store reconstituted solution at 2-8°C and use within 30 days. Lyophilized powder stable at -20°C for 24 months when sealed under inert atmosphere.
Every lot ships with a third-party HPLC certificate. View the most recent lot certificate via the COA Portal. Mass spectrometry confirmation available on request.
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