Ipamorelin
Selective pentapeptide GH secretagogue. ≥99% purity. 5mg lyophilized. GHS-R1a agonist studied for selective GH release without cortisol elevation.
Overview
Ipamorelin (Growth Hormone Secretagogue) is a synthetic pentapeptide growth hormone secretagogue. One of the most selective GH secretagogues studied, with minimal effects on cortisol and prolactin.
Published Research
Published literature has examined Ipamorelin across multiple research contexts:
- Selective GH release via ghrelin receptor (GHS-R1a) agonism
- Minimal cortisol and prolactin elevation compared to other secretagogues
- Pulsatile GH release patterns in preclinical models
- Bone mineral density and body composition research biomarkers
| Molecular Formula | C38H49N9O5 |
|---|---|
| Molecular Weight | 711.85 g/mol |
| Monoisotopic Mass | 711.38 Da |
| CAS Number | 170851-70-4 |
| Amino Acid Count | 5 |
| Sequence | Aib-His-D-2-Nal-D-Phe-Lys-NH2 |
| Purity | ≥99.3% (HPLC verified) |
| Physical Form | White lyophilized powder |
| Storage | -20°C recommended, protect from light |
| PubChem CID | 9831659 |
| SKU | IPAM |
• GH secretagogue biology: Studies have examined Ipamorelin's selective GHS-R1a activation and its specificity for GH release over other pituitary hormones (Raun et al., 1998).
• Bone biology: Preclinical studies have investigated Ipamorelin's effects on bone mineral density and osteoblast activity in ovariectomized rat models.
• GI motility: Research has examined ghrelin receptor-mediated effects on gastrointestinal transit in animal models.
• Neuroendocrine selectivity: Comparative studies examining Ipamorelin's endocrine profile versus GHRP-6 and GHRP-2.
Standard reconstitution: 1 mL bacteriostatic water per vial unless otherwise specified on the Certificate of Analysis. Store reconstituted solution at 2-8°C and use within 30 days. Lyophilized powder stable at -20°C for 24 months when sealed under inert atmosphere.
Every lot ships with a third-party HPLC certificate. View the most recent lot certificate via the COA Portal. Mass spectrometry confirmation available on request.
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