Sermorelin
Native GHRH(1-29) fragment (29 amino acids). ≥99% purity. 2mg lyophilized. Previously investigational diagnostic agent. GHRH receptor agonist for neuroendocrine research.
Overview
Sermorelin (GRF 1-29) is a synthetic analog of Growth Hormone Releasing Hormone (GHRH). Sermorelin is the biologically active fragment (first 29 amino acids) of the 44-amino acid GHRH.
Published Research
Published literature has examined Sermorelin across multiple research contexts:
- GHRH receptor agonism and pulsatile GH release stimulation
- Pituitary somatotroph cell activation in preclinical models
- Sleep architecture and slow-wave sleep research
- IGF-1 axis signaling pathway investigation
| Molecular Formula | C149H246N44O42S |
|---|---|
| Molecular Weight | 3357.88 g/mol |
| Monoisotopic Mass | 3356.82 Da |
| CAS Number | 86168-78-7 |
| Amino Acid Count | 29 |
| Sequence | Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2 |
| Purity | ≥99.0% (HPLC verified) |
| Physical Form | White lyophilized powder |
| Storage | -20°C recommended, protect from light |
| PubChem CID | 16132413 |
| SKU | SERM |
• Neuroendocrine research: Sermorelin has been used as a diagnostic tool for pituitary GH reserve assessment in clinical settings.
• GH axis biology: Studies have examined pulsatile GH release patterns and somatotroph responsiveness to GHRH stimulation.
• Aging research: Investigations into age-related changes in GHRH responsiveness and GH-IGF-1 axis function.
• Metabolic research: Studies on GH-mediated effects on body composition and metabolism.
Standard reconstitution: 1 mL bacteriostatic water per vial unless otherwise specified on the Certificate of Analysis. Store reconstituted solution at 2-8°C and use within 30 days. Lyophilized powder stable at -20°C for 24 months when sealed under inert atmosphere.
Every lot ships with a third-party HPLC certificate. View the most recent lot certificate via the COA Portal. Mass spectrometry confirmation available on request.
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