Semax
CAS
80714-61-0
Formula
C37H51N9O10
MW
813.93 g/mol
Sequence
Met-Glu-His-Phe-Pro-Gly-Pro
Form
White lyophilized powder
Storage
-20°C recommended, protect from light
Purity
≥99.2% HPLC
Neuropeptide Research

Semax

Synthetic ACTH(4–7) heptapeptide analog. ≥99% purity. Studied for BDNF/NGF expression and neurotrophic signalling in preclinical models.

99.2% HPLCLot AUR-2025-SEMCertificate of Analysis ↗
From Price range: $34.00 through $56.00

For Research Purposes Only • Not For Human Consumption

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Packs of 10 vials: $20.40 each after 3 orders (Atelier) · $17.00 each after 6 orders (Laboratory)

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For Research Use Only (RUO). Not for human or veterinary use. Not for diagnostic or therapeutic purposes. Not approved by the FDA. By purchasing, you acknowledge research-only intent.
✓99.2%+ HPLC Verified ✓Certificate of Analysis Included ✓Lyophilized for Stability ✓Same-Day Dispatch by 2 PM ET ✓SKU: SEMAX

Overview

Semax (ACTH 4-10 Analog) is a synthetic heptapeptide analog of ACTH (adrenocorticotropic hormone) fragment 4-10. Developed at the Institute of Molecular Genetics in Russia. Contains a Pro-Gly-Pro stabilizing sequence.

Published Research

Published literature has examined Semax across multiple research contexts:

  • BDNF (Brain-Derived Neurotrophic Factor) expression in preclinical models
  • Dopaminergic and serotonergic neurotransmitter system interactions
  • Neuropeptide processing and enkephalin degradation pathways
  • Cognitive function biomarkers in published preclinical literature
Chemical Profile · Analytical Specifications
Molecular FormulaC37H51N9O10
Molecular Weight813.93 g/mol
Monoisotopic Mass813.37 Da
CAS Number80714-61-0
Amino Acid Count7
SequenceMet-Glu-His-Phe-Pro-Gly-Pro
Purity≥99.2% (HPLC verified)
Physical FormWhite lyophilized powder
Storage-20°C recommended, protect from light
PubChem CID9811102
SKUSEMAX
Analytical data. Specifications reflect typical lot characteristics. Lot-specific values appear on the Certificate of Analysis shipped with each order. View the current lot certificate →

• Neurotrophic factor research: Studies have examined Semax effects on BDNF, NGF, and GDNF expression in neuronal cell cultures (Dolotov et al., 2006).
• Cognitive biology: Animal behavioral studies using Morris water maze and passive avoidance paradigms.
• Neuroprotection: Research in models of oxidative stress and ischemia-reperfusion in neuronal systems.
• Immune modulation: Studies examining effects on cytokine profiles and immune cell function.

Standard reconstitution: 1 mL bacteriostatic water per vial unless otherwise specified on the Certificate of Analysis. Store reconstituted solution at 2-8°C and use within 30 days. Lyophilized powder stable at -20°C for 24 months when sealed under inert atmosphere.

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Every lot ships with a third-party HPLC certificate. View the most recent lot certificate via the COA Portal. Mass spectrometry confirmation available on request.

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RESEARCH USE ONLY (RUO). Not for human or veterinary use. Not for consumption of any kind. Not for use in the diagnosis, treatment, cure, or prevention of any disease or condition. Not approved by the FDA. All products are sold exclusively to qualified research professionals aged 21 or older, for in-vitro laboratory research purposes only.No statement on this website has been evaluated by the FDA. By purchasing you confirm you are a qualified researcher and accept our Terms. California Proposition 65: products may contain chemicals known to the State of California to cause cancer or reproductive harm. P65Warnings.ca.gov

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