Semax
ACTH(4-7) heptapeptide analog. ≥99% purity. 5mg lyophilized. Studied for BDNF/NGF upregulation and neurotrophic activity. Registered pharmaceutical in Russia.
Overview
Semax (ACTH 4-10 Analog) is a synthetic heptapeptide analog of ACTH (adrenocorticotropic hormone) fragment 4-10. Developed at the Institute of Molecular Genetics in Russia. Contains a Pro-Gly-Pro stabilizing sequence.
Published Research
Published literature has examined Semax across multiple research contexts:
- BDNF (Brain-Derived Neurotrophic Factor) expression in preclinical models
- Dopaminergic and serotonergic neurotransmitter system interactions
- Neuropeptide processing and enkephalin degradation pathways
- Cognitive function biomarkers in published preclinical literature
| Molecular Formula | C37H51N9O10 |
|---|---|
| Molecular Weight | 813.93 g/mol |
| Monoisotopic Mass | 813.37 Da |
| CAS Number | 80714-61-0 |
| Amino Acid Count | 7 |
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro |
| Purity | ≥99.2% (HPLC verified) |
| Physical Form | White lyophilized powder |
| Storage | -20°C recommended, protect from light |
| PubChem CID | 9811102 |
| SKU | SEMAX |
• Neurotrophic factor research: Studies have examined Semax effects on BDNF, NGF, and GDNF expression in neuronal cell cultures (Dolotov et al., 2006).
• Cognitive biology: Animal behavioral studies using Morris water maze and passive avoidance paradigms.
• Neuroprotection: Research in models of oxidative stress and ischemia-reperfusion in neuronal systems.
• Immune modulation: Studies examining effects on cytokine profiles and immune cell function.
Standard reconstitution: 1 mL bacteriostatic water per vial unless otherwise specified on the Certificate of Analysis. Store reconstituted solution at 2-8°C and use within 30 days. Lyophilized powder stable at -20°C for 24 months when sealed under inert atmosphere.
- Purity (HPLC)
- 99.2%
- Identity (MS)
- 813.93 g/mol (theoretical)
Every vial of this lot carries this lot number and a QR code that resolves to the same page. Values are lot-specific analytical results; representative specifications are on the Specifications tab.
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