IGF-1 LR3
CAS
946870-92-4
Formula
C400H625N111O115S9
MW
~9111
Form
White lyophilized powder
Storage
-20°C recommended, protect from light
Purity
≥98.5% HPLC
Somatotropic Research

IGF-1 LR3

83-amino-acid IGF-1 analog with reduced IGFBP binding. ≥98% purity. A widely cited cell-culture supplement in proliferation and differentiation studies.

98.5%+ HPLC Verified · Lot COA Available
From Price range: $39.00 through $111.00

For Research Purposes Only • Not For Human Consumption

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3+—−15%
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  • Lot-specific COA, QR-verifiable
  • Lot number on your order line
  • Dispatched from the United States

Packs of 10 vials: $23.40 each after 3 orders (Atelier) · $19.50 each after 6 orders (Laboratory)

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For Research Use Only (RUO). Not for human or veterinary use. Not for diagnostic or therapeutic purposes. Not approved by the FDA. By purchasing, you acknowledge research-only intent.
✓98.5%+ HPLC Verified ✓Certificate of Analysis Included ✓Lyophilized for Stability ✓Same-Day Dispatch by 2 PM ET ✓SKU: IGF1LR3

Overview

IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is a modified IGF-1 with an arginine substitution at position 3 and a 13-amino acid N-terminal extension. Modified form of IGF-1 with reduced IGF binding protein affinity and extended half-life.

Published Research

Published literature has examined IGF-1 LR3 across multiple research contexts:

  • Reduced IGFBP binding resulting in increased bioavailability in research models
  • IGF-1 receptor activation and downstream PI3K/Akt signaling
  • Cell proliferation and differentiation pathway studies
  • Myogenic and metabolic research biomarker analysis
Chemical Profile · Analytical Specifications
Molecular FormulaC400H625N111O115S9
Molecular Weight~9111 g/mol
CAS Number946870-92-4
Amino Acid Count83
Purity≥98.5% (HPLC verified)
Physical FormWhite lyophilized powder
Storage-20°C recommended, protect from light
SKUIGF1LR3
Analytical data. Specifications reflect typical lot characteristics. Lot-specific values appear on the Certificate of Analysis shipped with each order. View representative COA →

• Cell culture: Widely used as a cell culture supplement to promote cell proliferation and inhibit apoptosis.
• IGF receptor biology: Studies on IGF-1R signaling pathways with reduced IGFBP interference.
• Growth factor research: Investigations into IGF-1 signaling in muscle, bone, and metabolic models.
• Stem cell biology: Used in various stem cell maintenance and differentiation protocols.

Standard reconstitution: 1 mL bacteriostatic water per vial unless otherwise specified on the Certificate of Analysis. Store reconstituted solution at 2-8°C and use within 30 days. Lyophilized powder stable at -20°C for 24 months when sealed under inert atmosphere.

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Every lot ships with a third-party HPLC certificate. View the most recent lot certificate via the COA Portal. Mass spectrometry confirmation available on request.

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Free shipping on orders over $49, bacteriostatic water included. Orders placed before 2 PM ET dispatch same business day from Salt Lake City via FedEx 2Day. International shipping via DHL Express. Returns accepted for damaged or short-shipped product within 30 days of delivery.

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IGF-1 LR3
IGF-1 LR3
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RESEARCH USE ONLY (RUO). Not for human or veterinary use. Not for consumption of any kind. Not for use in the diagnosis, treatment, cure, or prevention of any disease or condition. Not approved by the FDA. All products are sold exclusively to qualified research professionals aged 21 or older, for in-vitro laboratory research purposes only.No statement on this website has been evaluated by the FDA. By purchasing you confirm you are a qualified researcher and accept our Terms. California Proposition 65: products may contain chemicals known to the State of California to cause cancer or reproductive harm. P65Warnings.ca.gov

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IGF-1 LR3
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