CJC-1295 No DAC
Modified GRF 1-29 (29 amino acids). ≥99% purity. 2mg lyophilized. DPP-IV resistant GHRH analog for growth hormone axis research.
Overview
CJC-1295 No DAC (Mod GRF 1-29) is a synthetic analog of Growth Hormone Releasing Hormone (first 29 amino acids) without Drug Affinity Complex. Modified GRF 1-29 with amino acid substitutions for enhanced stability.
Published Research
Published literature has examined CJC-1295 No DAC across multiple research contexts:
- GHRH receptor agonism with improved metabolic stability over native GRF
- Pulsatile GH release pattern research (shorter duration than DAC version)
- Synergistic effects when studied alongside GHRP compounds
- Somatotroph cell activation and GH secretion dynamics
| Molecular Formula | C152H252N44O42 |
|---|---|
| Molecular Weight | 3367.97 g/mol |
| Monoisotopic Mass | 3366.89 Da |
| CAS Number | 863288-34-0 |
| Amino Acid Count | 29 |
| Sequence | Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2 |
| Purity | ≥99.1% (HPLC verified) |
| Physical Form | White lyophilized powder |
| Storage | -20°C recommended, protect from light |
| SKU | CJC1295-NODAC |
• GHRH receptor biology: Studies have examined CJC-1295's interaction with the GHRH receptor (GHRHR) and downstream somatotroph signaling.
• GH secretion research: Investigations into pulsatile GH release patterns and the synergistic effects with ghrelin-mimetic peptides.
• Metabolic research: Studies examining GH axis modulation and associated effects on lipolysis and nitrogen balance in animal models.
• Neuroendocrine research: Investigations into hypothalamic-pituitary axis feedback mechanisms.
Standard reconstitution: 1 mL bacteriostatic water per vial unless otherwise specified on the Certificate of Analysis. Store reconstituted solution at 2-8°C and use within 30 days. Lyophilized powder stable at -20°C for 24 months when sealed under inert atmosphere.
Every lot ships with a third-party HPLC certificate. View the most recent lot certificate via the COA Portal. Mass spectrometry confirmation available on request.
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