TB-500
Thymosin Beta-4 analog (43 amino acids). ≥99% purity. 5mg lyophilized. Studied for cell migration, angiogenesis, and actin-sequestering activity in preclinical research.
Overview
TB-500 (Thymosin Beta-4 Fragment) is a synthetic 43-amino acid peptide fragment of Thymosin Beta-4. Extensively studied for its role in actin regulation and cell migration.
Published Research
Published literature has examined TB-500 across multiple research contexts:
- Actin-binding and sequestration in preclinical cellular models
- Cell migration and differentiation pathways in published literature
- Interaction with inflammatory signaling cascades in preclinical models
- Extracellular matrix remodeling and tissue organization research
| Molecular Formula | C212H350N56O78S |
|---|---|
| Molecular Weight | 4963.44 g/mol |
| Monoisotopic Mass | 4960.5 Da |
| CAS Number | 885340-08-9 |
| Amino Acid Count | 43 |
| Sequence | SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES |
| Purity | ≥99.1% (HPLC verified) |
| Physical Form | White lyophilized powder |
| Storage | -20°C recommended, protect from light |
| PubChem CID | 62707662 |
| SKU | TB500-2MG |
• Wound biology: Preclinical studies have examined Tβ4's effects on keratinocyte and endothelial cell migration in scratch-wound assays (Malinda et al., 1999).
• Cardiac biology: Animal models of myocardial infarction have been used to study Tβ4's effects on cardiomyocyte survival and epicardial progenitor activation (Smart et al., 2007).
• Ocular biology: Research in corneal wound models has investigated Tβ4's effects on epithelial healing and inflammation (Sosne et al., 2005).
• Musculoskeletal research: Studies have assessed TB-500 in tendon and muscle injury models in rodents.
Standard reconstitution: 1 mL bacteriostatic water per vial unless otherwise specified on the Certificate of Analysis. Store reconstituted solution at 2-8°C and use within 30 days. Lyophilized powder stable at -20°C for 24 months when sealed under inert atmosphere.
Every lot ships with a third-party HPLC certificate. View the most recent lot certificate via the COA Portal. Mass spectrometry confirmation available on request.
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