Sterile 0.6% acetic acid solution is a specialized peptide reconstitution solvent used for peptides with high isoelectric points that may not dissolve readily in neutral pH bacteriostatic water. The acidic pH (~3.0) protonates basic residues and improves solubility for peptides such as IGF-1 LR3 and other basic or hydrophobic research compounds.
Biochemical Characteristics
Specifications
Molecular Formula
CH3COOH (diluted)
CAS Number
64-19-7
0.6% acetic acid in sterile water provides a pH of approximately 3.0. At this pH, basic amino acid residues (Arg, Lys, His) are fully protonated, increasing the net positive charge of basic peptides and enhancing their aqueous solubility.
This is the standard reconstitution solvent for peptides with isoelectric points above 7.0 that show poor solubility in neutral water.
Tested for sterility, acetic acid concentration, pH, and endotoxin.
Article Author
DS
Article Author
Dr. Sarah Chen, Ph.D.
Biochemistry researcher specializing in peptide formulation.
This content was prepared for informational purposes based on published reference standards.
Citations
1
USP. "Acetic Acid." USP-NF Monograph. PubMed
2
Fields GB, Noble RL. "Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids." Int J Pept Protein Res. 1990;35(3):161-214. PubMed
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Properties
Molecular Formula
CH3COOH (diluted)
99.9%
HPLC Purity
Target: ≥98%
Janssen Analytical Laboratories
Salt Lake City, UT 84101
Verified
Test
Target
Result
Sterility (USP <71>)
No growth
Pass ✓
Acetic Acid Concentration
0.6% u00b1 0.1%
0.6% ✓
pH
2.8-3.2
3.0 ✓
Endotoxin (LAL)
<0.25 EU/mL
<0.1 EU/mL ✓
Temperature
Store at controlled room temperature: 20-25°C (68-77°F)
Do not freeze
Shelf Life
24 months sealed at room temperature
28 days after opening
Handling
Use for peptides not soluble in bacteriostatic water.
Swab stopper with alcohol before each use.
Discard 28 days after first puncture.
Frequently Asked Questions
Acetic Acid 0.6% is verified at ≥99.9% purity via reverse-phase HPLC analysis. Each batch also undergoes ESI mass spectrometry for identity confirmation, LAL endotoxin testing (<0.1 EU/mg), and USP <71> sterility testing. A batch-specific Certificate of Analysis (COA) is included with every order.
Lyophilized (powder): Store at -20°C, protected from light and moisture. Shelf life: 24 months. Reconstituted (solution): Store at 2-8°C, use within 30 days. Critical: Allow the vial to reach room temperature before opening to prevent moisture condensation inside the vial. Avoid repeated freeze-thaw cycles (max 3 recommended).
The CAS registry number for Acetic Acid 0.6% is 64-19-7. Molecular formula: CH3COOH (diluted). Full chemical characterization data including PubChem identifiers, SMILES notation, and InChIKey are available on the Chemical Properties tab above.
Yes. Every batch of Acetic Acid 0.6% is independently tested by Janssen Analytical Laboratories (ISO 17025-accredited). Testing includes HPLC purity analysis, mass spectrometry identity confirmation, LAL kinetic turbidimetric endotoxin assay, and USP <71> sterility testing. Full results are provided in the batch-specific COA. Additional documentation is available on the COA/HPLC/MS and 3rd Party Testing tabs above.
Orders placed before 2:00 PM EST ship same day via cold-chain logistics with gel ice packs to maintain product integrity during transit. Most domestic orders arrive within 2-4 business days. Full tracking is provided. All vials are sealed under inert atmosphere and packaged to prevent damage.
Yes. Tiered pricing is applied automatically at checkout: 2+ units at 10% off, 3+ units at 15% off, and 5+ units at 20% off. For institutional or bulk research inquiries (10+ vials), contact us at contact@aureumpeptides.com for custom pricing.
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