44-amino acid GHRH analog with N-terminal modification. ≥99% purity. 2mg lyophilized. FDA-approved as Egrifta. Research-grade for in vitro investigation.
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Tesamorelin is a synthetic 44-amino acid analog of human growth hormone-releasing hormone (GHRH) with a trans-3-hexenoic acid modification at the N-terminus. FDA-approved as Egrifta for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. This research-grade material is for in vitro investigation only.
Biochemical Characteristics
Specifications
Molecular Formula
C221H366N72O67S
Molecular Weight
~5135.7 g/mol
CAS Number
218949-48-5
Tesamorelin has an approximate molecular weight of 5135.7 g/mol. The trans-3-hexenoic acid N-terminal modification enhances resistance to DPP-IV degradation while maintaining full GHRHR agonist activity. It represents the full-length GHRH(1-44) sequence with this single modification.
Research Applications
• GHRH receptor biology: Studies on GHRHR activation and downstream somatotroph signaling.
• Lipodystrophy: Clinical research on visceral adipose tissue reduction.
• GH-IGF-1 axis: Studies examining pulsatile GH release and IGF-1 elevation patterns.
• Metabolic research: Investigations into GH-mediated lipolysis.
Form & Analytical Testing
Form: Lyophilized powder, 2mg per vial
Appearance: White powder
Solubility: Soluble in sterile water
Full analytical testing per batch.
Article Author
DS
Article Author
Dr. Sarah Chen, Ph.D.
Biochemistry researcher specializing in neuroendocrine peptide pharmacology.
This content was prepared for informational purposes based on published preclinical research. It does not constitute medical advice or product efficacy claims.
Citations
1
Falutz J, et al. "Metabolic effects of a growth hormone-releasing factor in patients with HIV." N Engl J Med. 2007;357(23):2359-70. PubMed
RUO Disclaimer
ALL ARTICLES AND PRODUCT INFORMATION ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. Products are for in-vitro studies only. Not approved by the FDA. Bodily introduction strictly forbidden. These products are not drugs, supplements, food, or cosmetics and may not be acquired for such purposes.
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Lyophilized: -20°C, protected from light
Reconstituted: 2-8°C
Shelf Life
24 months lyophilized at -20°C
14 days reconstituted at 2-8°C
Handling
Allow vial to reach room temperature before opening.
Reconstitute with sterile water.
Avoid repeated freeze-thaw cycles.
Frequently Asked Questions
Tesamorelin is verified at ≥99.0% purity via reverse-phase HPLC analysis. Each batch also undergoes ESI mass spectrometry for identity confirmation, LAL endotoxin testing (<0.1 EU/mg), and USP <71> sterility testing. A batch-specific Certificate of Analysis (COA) is included with every order.
Add bacteriostatic water (0.9% benzyl alcohol) slowly to the vial wall. Gently swirl to dissolve — do not shake or vortex. Solubility: Soluble in sterile water. Reconstituted peptide should be stored at 2-8°C and used within 30 days. For single-use applications, sterile water may be substituted (no preservative, use immediately).
Lyophilized (powder): Store at -20°C, protected from light and moisture. Shelf life: 24 months. Reconstituted (solution): Store at 2-8°C, use within 30 days. Critical: Allow the vial to reach room temperature before opening to prevent moisture condensation inside the vial. Avoid repeated freeze-thaw cycles (max 3 recommended).
The CAS registry number for Tesamorelin is 218949-48-5. Molecular weight: ~5135.7 g/mol. Molecular formula: C221H366N72O67S. Full chemical characterization data including PubChem identifiers, SMILES notation, and InChIKey are available on the Chemical Properties tab above.
Yes. Every batch of Tesamorelin is independently tested by Janssen Analytical Laboratories (ISO 17025-accredited). Testing includes HPLC purity analysis, mass spectrometry identity confirmation, LAL kinetic turbidimetric endotoxin assay, and USP <71> sterility testing. Full results are provided in the batch-specific COA. Additional documentation is available on the COA/HPLC/MS and 3rd Party Testing tabs above.
Orders placed before 2:00 PM EST ship same day via cold-chain logistics with gel ice packs to maintain product integrity during transit. Most domestic orders arrive within 2-4 business days. Full tracking is provided. All vials are sealed under inert atmosphere and packaged to prevent damage.
Yes. Tiered pricing is applied automatically at checkout: 2+ units at 10% off, 3+ units at 15% off, and 5+ units at 20% off. For institutional or bulk research inquiries (10+ vials), contact us at contact@aureumpeptides.com for custom pricing.
Compatibility depends on your specific experimental design. Tesamorelin is provided as a single-compound lyophilized preparation for maximum flexibility. When using multiple compounds, reconstitute each separately and add to experimental systems independently to avoid potential interactions during reconstitution. Check the "Researchers Also Purchased" section below for commonly paired research compounds.
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Tesamorelin$32.00–$107.00Price range: $32.00 through $107.00
CA Prop 65: WARNING: This product can expose you to chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm. P65Warnings.ca.gov
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All products are sold strictly for in vitro research and laboratory use. Not for human consumption, therapeutic use, or veterinary use. No statements on this website have been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you confirm you are a qualified researcher and agree to our Terms of Service. CA Prop 65 Warning: Products may contain chemicals known to the State of California to cause cancer or reproductive harm.
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